Estradiol is a naturally occurring sex hormone and is the strongest of the three major estrogens produced by the human body. It plays an essential role in sexual and reproductive development, mainly in women.
Specifically, estradiol has several key functions:
Now, from where does this estradiol come? Well, it is mainly secreted by the ovaries in women. The production begins during puberty, varies through the menstrual cycle, declines with menopause, and finally stops.
In men and postmenopausal women, estradiol originates from testosterone conversion. Aromatase enzymes in tissues like fat, skin, brain etc. catalyze this conversion reaction.
To summarize - estradiol serves reproductive, mental, and overall well-being purposes in women. It characterizes female anatomy and physiology. The ovaries secrete estradiol in a well-coordinated manner with other sex hormones. An imbalance can disrupt menstrual cycles or cause problems like infertility, osteoporosis, etc. Hence, it is important to maintain optimal estradiol levels through lifestyle measures like regular exercise, a healthy diet, and stress management. Supplementation may also be needed sometimes.
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